Metabolic Pathway Builder 3.7

Genostar has integrated new cutting-edge technology and algorithms throughout the Metabolic Pathway Builder software suite. These new features make your exploration of the microbial world not only faster, but also more accurate, interactive and visual.

GenoAnnot has extended annotation functionalities.

The comparison of your contigs against sequences of reference species has been improved, with the detection of exact matches from which complete genomes can be assembled. This functionality facilitates the detection of species-specific zones and even single nucleotide polymorphism which is particularly useful in virulence research. Results can be displayed in an improved map viewer and in tabular form.

The module has also been optimized for re-annotation and the prediction of potential genes through the computation of overlapping features. Read more

ProteoAnnot has improved databank management functionality, rendering the integration and sharing of proprietary and public databanks easier throughout the module. In addition the import functionality has been extended, so that each newly created databank is now automatically provided with functional annotations. Thanks to the latter, you can now associate polypeptides with functional classifications. Read more

PathwayExplorer's protein import functionality has been extended, facilitating research on cleaved, multifunctional and new proteins. Establish links between in vivo outcomes of experiments to in silico data in the Workspace through protein name identification. With the improved KEGG maps, you can now even compare metabolisms. Read more

Genomic Viewer has been improved with the visualization of the GC content and the GC skew, facilitating the visual detection of insertions and origins of replication. In addition, bookmark functionality has been added, helping to memorize interesting genomic regions. Also navigation through genomic maps has been improved with shortcuts. Read more

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Detailed description of new features

New Features of GenoAnnot

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	Compare genomic data (improved) between a reference sequence and contigs, between two sequences or between two sets of sequences find exact matches with minimum length using MUMmer detect specific regions and SNPs create assembled sequence relative to reference sequences
	Transfer annotations (improved) between CDSs with homology relationship calculate BlastP homologies filter relevant homologies, using hit and query coverage, and the BlastP result values
	Compute overlapping features automatically detect overlapping features (such as CDSs or Blast hits) on a sequence verify/confirm predicted CDSs using Blast hits detect potential genes
	Modify the start position of CDSs Relocate the start position of a CDSs in function of a Blast hit or a prediction
	Manage Blast databanks create a databank from data files (FASTA, UniProt) or from organisms of your workspace or from the MicroB database customize your protein datasets with functional annotation from GO, EC, PFAM, PDB or PROSITE share your Blast databanks delete a databank

New Features of ProteoAnnot

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Manage Blast databank

create a databank from data files (FASTA, UniProt) or from organisms of your workspace or of the MicroB database
customize your protein datasets with functional annotation from GO, EC, PFAM, PDB or PROSITE.
share your Blast databanks
delete a databank